TBR1 and autism spectrum disorder: T-Brain-1 (TBR1), a causative gene of autism spectrum disorders (ASD) (Neale et al., 2012; O'roak et al., 2012a,b; de Rubeis et al., 2014; Sanders et al., 2015), is a brain-specific transcriptional factor involved in AC formation (Huang et al., 2014, 2019b).