Importantly, haploinsufficiency or ASD-linked mutation of Tbr1 also results in autism-like behaviors in mice, including reduced social interaction, impaired amygdala-dependent associative memory and disrupted olfactory discrimination (Huang et al., 2014, 2019a; Yook et al., 2019), highlighting the relevance of TBR1 deficiency in ASD and reinforcing the potential role of the AC in neuropsychiatric disorders. The gene discussed is TBR1; the disease is autism.