MKI67 and astrocytoma (excluding glioblastoma): It is well known that an increased Ki67 index is associated with a higher grade of astrocytomas.20 Nevertheless, to date, studies of the independent prognostic value of the Ki67 index in glioma have revealed conflicting results.21 Herein, the correlation between the Ki67 index and the pathologic grades or overall survival of patients with glioma were analyzed.