Thus, sPD-L1 is an effective predictor of DLBCL.382 In PTCL, PD-1 is positive in 70% and 61% of AITL and PTCL-NOS, respectively, and PD-1 is rarely detected in ALCL. This evidence concerns the gene SPDL1 and mature T-cell and NK-cell non-Hodgkin lymphoma.