EGFR (epidermal growth factor receptor) overexpression is commonly correlated with the development of many cancers, including prostate cancer.112 PIM1 expression is correlated with EGFR expression in head and neck cancer, in which anti-EGFR treatment (cetuximab and gefitinib) prevented the EGFR-stimulated translocation of PIM1 (ref. 113). This evidence concerns the gene PIM1 and Familial prostate cancer.