JUN and hematopoietic and lymphoid system neoplasm: Based on the cellular effects observed after NT157 treatment and the description of these genes in hematologic neoplasms, four repressed oncogenes (CCND1, MYB, WT1, and NFKB1) and three upregulated apoptosis-related genes (CDKN1A, FOS, and JUN) were selected and validated in a larger number of experiments (n = 5) (all p < 0.05) (Fig. 3b).