ANXA5 and age-related macular degeneration: Previous in vitro AMD studies have reported the existence of apoptosis and necrosis in oxidant-induced RPE injury.9,17 In this study, to reveal the exact effect of D609 in SI-induced RPE injury, we performed propidium iodide (PI)/annexin V flow cytometry to elucidate the cell death types following treatment of each group.