There is the highest degree of similarity (~40–70%) at the carboxy-terminal regions among mature peptides that are the biologically active form of BMP-7 and TGF-β1.13 To date, no less than fifteen BMPs have been identified.14 Recently, more attention has been focused on BMP-7, which is also known as osteogenic protein-1 (OP-1), for its protective role in acute and chronic kidney diseases. This evidence concerns the gene BMP7 and chronic kidney disease.