The variables associated with the PASS status in the univariate analysis (p < 0.10) were age (OR 1.02), secondary education (OR 0.45), active workers (OR 2.23), retired (OR 2.72), smoking (OR 0.46), peripheral disease (OR 2.03), DIP involvement (OR 0.64), PsA family history (OR 0.52), coronary heart disease (OR 7.02), obesity (OR 1.73), CRP (OR 0.94), glucocorticoids (OR 0.45), and syndesmophytes (OR 0.44). The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.