Elevated circulating levels of galectin-3 correlate with early myocardial infarction, predict long-term cardiovascular death in high-risk patients with coronary artery disease,65 and serve as an independent indicator of increased risk of all-cause mortality in patients after myocardial infarction,66 suggesting that galectin-3 within the circulation is a biomarker of cardiovascular disease. This evidence concerns the gene LGALS3 and cardiovascular disorder.