MOG and experimental autoimmune encephalomyelitis: In a myelin oligodendrocyte glycoprotein-specific t cell receptor (MOG-TCR) transgenic mouse model of spontaneous disease, experimental autoimmune encephalomyelitis (EAE) does not occur under germ-free (GF) conditions, whereas mice transferred from GF conditions into a conventional environment develop spontaneous EAE after few weeks of transfer [40].