The Face2Gene system evoked a few other syndromes with some resemblance to the SLC39A13 phenotype, such as Noonan syndrome (downslanting palpebral fissures), Stickler syndrome (flat face; associated with COL2A1 haploinsufficiency), as well as—interestingly—the vascular type of EDS (EDS IV; dominant COL3A1), probably because of the “hollow eyes”. Here, COL3A1 is linked to Ehlers-Danlos syndrome.