To determine whether blocking PD-1 with anti-PD-1 antibody inhibits SCC VII tumor growth, we challenged mice with SCC VII cells s.c. and then injected them with anti-PD-1 antibody (Clone RMP1-14;200 μg/dose) intraperitoneally (i.p.)starting eight days after tumor challenge. Here, PDCD1 is linked to neoplasm.