NR4A1 and breast cancer: Liu et al. [53] found that in patients with hormone receptor-negative BC, a high NLR was associated with a poor OS in the univariate (HR = 3.09; 95%CI 2.35–4.06; p < 0.001) and multivariate analyses (HR = 3.09; 95%CI 2.35–4.06; p < 0.001).