Xie et al. [9] demonstrated a significant upregulation of H19 expression in the TGF-β-induced fibrosis of human proximal tubular epithelial cells and UUO-induced renal fibrosis, and that the knockdown of H19 significantly attenuates renal fibrosis in vitro and in vivo. This evidence concerns the gene TGFB1 and renal fibrosis.