DPP4 is upregulated in many aggressive types of T-cell malignancies (9), esophageal adenocarcinoma (10), lung adenocarcinoma (11), thyroid carcinoma (12), and prostate cancer (13), and a high level of DPP4 is indicative of poor prognosis for papillary thyroid carcinoma (14), urothelial carcinoma (15), and colorectal cancer (16). This evidence concerns the gene DPP4 and thyroid gland carcinoma.