Additionally, the results of western blotting and qRT-PCR suggested that the miR-21 mimic and PTEN inhibitor could restore the EMT progression of HCC cells that was inhibited by puerarin; the miR-21 mimic and PTEN inhibitor restored the downregulation of E-cadherin and upregulation of N-cadherin and vimentin (Figure 6C and D). This evidence concerns the gene CDH1 and hepatocellular carcinoma.