FLT3 and acute myeloid leukemia: In this study, the duration of the first CR, allogeneic SCT during first-line therapy, age, and FLT3-ITD were reported as unfavorable factors for survival, whereas higher duration of the first CR, biallelic CEBPA mutation, core binding factor AML, and allogeneic HCT as treatment of relapse were favorable parameters for survival after relapse 38.