While neutrophils clearly underwent citrullination of Histone H3 during Zymosan-induced peritonitis, the fact that PAD4 inhibition led to a near-complete abrogation of neutrophil aggregation within FALCs did not allow us to conclude whether PAD4 was involved in the formation of the CitH3+ DNA outer-layer we observed. The gene discussed is PADI4; the disease is peritonitis.