Although providing an average incidence of PD-L1 expression in our combined sarcoma cohort is not biologically relevant, in view of the different molecular signature of the different subytpes of soft tissue sarcomas[20, 23], PD-L1 was present in 13% of all cases in which was the protein essentially only identified in tumour cells and not in immune cells when assessed primarily on TMAs. This evidence concerns the gene CD274 and soft tissue sarcoma.