In line with this finding, Kaplan‐Meier analysis demonstrated that strong Ubqln2 staining was also significantly correlated with unfavorable OS in HCC patients (Figure 2B, log‐rank test, P < .0001), indicating that Ubqln2 is a key factor in the prognosis of HCC. This evidence concerns the gene UBQLN2 and hepatocellular carcinoma.