Surprisingly, high Ubqln2 expression contributed approximately 78 points to survival prediction, which was much higher than the points contributed by many other features, indicating that HCC patients with high expression of Ubqln2 are apt to have a poor prognosis and short survival and hinting that inhibition of Ubqln2 may greatly reduce risks. This evidence concerns the gene UBQLN2 and hepatocellular carcinoma.