Our research on the oncogenic role of LINC00483 in gastric cancer showed that silence of LINC00483 repressed progression of gastric cancer in vitro and in vivo, possibly by acting as a sponge of miR-490-3p to regulate MAPK1, which provided a new mechanism for development of gastric cancer and indicated a novel target for treatment of gastric cancer. Here, MAPK1 is linked to gastric cancer.