NFκB levels decreased in both diet groups (main effect of challenge (F(3,20) = 4.44, p < 0.05), Fig. 8e), where as IL6/IL10 ratio decreased in CHD males (main effect of challenge (F(3,20) = 4.458, p<0.05), Scheffe post hoc p = 0.024), but remained unchanged in HFD offspring (Scheffe post hoc p = 0.276, Fig. 8f). The gene discussed is NFKB1; the disease is coronary artery disorder.