Also in the hippocampus, MKP1 increased in HFD offspring (main effect of challenge (F(3,20) = 12.75, p < 0.05), Scheffe post hoc p = 0.001), but remained unchanged in CHD offspring (Scheffe post hoc p = 0.985, Fig. 3e). The gene discussed is DUSP1; the disease is coronary artery disorder.