A large proportion (47 RBPs) are commonly regulated in both RSCC and LSCC with several enriched for binding among DEGs (adj p < 0.05, see Methods), including RBPs previously discussed in the context of CRC such MSI2, MEX3A, IGF2BP1/3, ELVAL4 [55, 56], and cancers in general, such as RBM47, DKC1, CELF4, ELAVL3 (Fig. 7e, Supplementary Table S11). This evidence concerns the gene CELF4 and cancer.