ABCA1 and ischemic stroke: Fourteen studies containing 2865 cases and 3227 controls were included in the meta-analysis and the results suggested that there is a strong association between ABCA1 R219K and the ischemic stroke risks (K vs. R: OR = 0.837, 95% CI: 0.735- 0.954, p=0.008; KK vs. RR: OR = 0.689, 95% CI: 0.520-0.912, p=0.009; KK+RK vs. RR: OR = 0.782, 95% CI: 0.691-0.885, p<0.001).