ABCA1 and ischemic stroke: As shown in Table 2, ABCA1 R219K was significantly associated with ischemic stroke for the allelic model (K vs. R: OR = 0.837, 95% CI: 0.735- 0.954, p=0.008), the homozygotic model (KK vs. RR: OR = 0.689, 95% CI: 0.520-0.912, p=0.009) and the dominant model (KK+RK vs. RR: OR = 0.782, 95% CI: 0.691-0.885, p<0.001) (Fig. 2), but not the recessive model (KK vs. RK+RR: OR =0.772, 95% CI: 0.594-1.003, p=0.053).