A singular GWAS study of a Japanese adult-onset asthma population showed that SNPs of HLA-, thymic stromal lymphopoietin-WD repeat domain 36 (TSLP-WDR36)-, and ubiquitin specific peptidase 38-GRB2 associated binding protein 1 (USP38-GAB1) loci are associated with adult-onset asthma (Hirota et al., 2011). This evidence concerns the gene GAB1 and adult onset asthma.