Expression profiles reassembled in nasal and bronchial brushings, were specific to asthma independently of atopic status, and clustering analysis identified Th2-high and low subjects differentiated by expression of 70 genes (such as IL-13, IL-5, periostin, CLCA1, SERPINB2) (Poole et al., 2014). The gene discussed is IL13; the disease is asthma.