To further investigate the prognostic value of SLFN11 expression in HCC, IHC analysis was used to assess TMA from patients in the Fudan LCI cohort 1 (N = 182) and Fudan LCI cohort 2 (N = 110) with complete clinicopathologic characteristics and follow-up data. This evidence concerns the gene SLFN11 and hepatocellular carcinoma.