SLFN11 and hepatocellular carcinoma: In addition, results from transwell assays indicated that the migratory and invasive capacities were greatly hindered by overexpression of SLFN11 in HCCLM3 and Hep3B cells, whereas SLFN11 KD HCC cells had significantly higher cell migratory and invasive capacities than did control cells (Figure 2E,Figure S3E).