At day 22 after the start of therapy, all animals within the NaCl + 41 °C + NaCl group had to be sacrificed based on tumor growth, whereas 100% of the HSP70B-NIS-MSCS + 41 °C + 131I and 70% of the HSP70B-NIS-MSCS + 37 °C + 131I groups were still alive. The gene discussed is HSPA7; the disease is neoplasm.