ALDH2 and cardiac arrest: Thus, the aims of this study are (1) to evaluate the effect of enhanced activity or expression of ALDH2 on myocardial dysfunction and survival after cardiac arrest, (2) to examine the importance of ALDH2 in reducing cardiomyocyte death and mitochondrial injury, and (3) to elucidate the underlying mechanisms by which ALDH2 exerts cardioprotection with a focus on mitochondrial ROS production.