BDNF and juvenile Huntington disease: In addition, regulation of BDNF expression levels by miRNA-10a-5p has been reported previously in granulosa cells of the ovary [56] and cervical cancer cells [45]; this miRNA was also differentially expressed in the cerebrospinal fluid of Alzheimer’s and Parkinson’s disease patients [57] as well as in brain tissue samples from Huntington’s disease patients [58].