Chi-Square tests showed no relationship of the presence of fever with any of the following factors: gender (p = 0.59), disease (melanoma, lung cancer, lymphoma, or other cancers; p = 1.00), ICI (anti-CTLA4, anti-PD1 or a combination of both; p = 0.69), other irAE (no other irAE or more than 1 irAE; p = 1.00), or onset of neutropenia (< 10 weeks or > 10 weeks; p = 0.07). Here, PDCD1 is linked to Decreased total neutrophil count.