Moreover, rs3748079, a SNP located in the promoter region of ITPR3, has been associated with several autoimmune diseases including systemic lupus erythematosus, rheumatoid arthritis, and Graves’ disease in a Japanese population [93], and the variant rs999943 of ITPR3 has been linked to obesity [94]. The gene discussed is ITPR3; the disease is rheumatoid arthritis.