Moreover, phosphorylation of protein kinase C delta PKC-delta, Janus kinase 1 (JAK1), and Janus kinase 2 (JAK2), which are the upstream activators of STAT1 are also inhibited by EGCG in interferon gamma (IFNγ)-stimulated oral cancer cells (shown in Figure 1) [5]. The gene discussed is JAK2; the disease is lip and oral cavity carcinoma.