No difference with respect to HF severity could be detected between patients who underwent invasive hemodynamic assessment and patients who did not (NYHA class ≥ III: n = 30.0 (49.2) % vs. n = 38.0 (36.2%), p = 0.106; median NT-proBNP: 3552 pg/mL (IQR: 1501–7357) versus 2972 pg/mL (IQR: 1238–6801), p = 0.478). This evidence concerns the gene NPPB and hydrops fetalis.