Compared to AKI + IA saline group, those treated with IA EVs showed upregulation of Ki67 (0.2 ± 0.1 vs. 0.4 ± 0.1 relative expression, p > 0.05) and FGF2 (0.4 ± 0.1 vs. 1.9 ± 0.3 relative expression, p < 0.05), as well as downregulation of FGF23 (2.1 ± 0.5 vs. 0.5 ± 0.1 relative expression, p < 0.05). The gene discussed is MKI67; the disease is acute kidney injury.