Immunohistochemical staining of the kidney showed that compared to untreated controls, those in the AKI + IA saline group had lower expression of proliferation markers FGF2 and Ki67 (9.2 ± 1.9% vs. 3.8 ± 0.8% Ki67+, p > 0.05) (Figure 4A). This evidence concerns the gene MKI67 and acute kidney injury.