FGF2 and kidney disorder: Compared to untreated controls, animals in the AKI + IA saline group had downregulation of Ki67 (0.6 ± 0.2 vs. 0.2 ± 0.1 relative expression, p > 0.05) and FGF2 protein (1.7 ± 0.6 vs. 0.4 ± 0.1 relative expression, p > 0.05), as well as upregulation of FGF23, a marker of kidney disease (0.5 ± 0.2 vs. 2.5 ± 0.5 relative expression, p < 0.05) (Figure 4B).