Compared with the AKI + IA saline group, those treated with IA EVs had significantly reduced BUN (151.32 ± 13.59 vs. 48.28 ± 5.87 mg/dL, p < 0.05) and SCr (3.95 ± 0.43 vs. 1.67 ± 0.30 mg/dL, p < 0.05) as well as decreased NGAL which did not reach statistical significance (4.26 ± 1.36 vs. 3.47 ± 0.94 mg/mL, p > 0.05). Here, LCN2 is linked to acute kidney injury.