Compared to the AKI + IA saline group, those treated with IA EVs had downregulation of NF-κB protein (3.6 ± 0.6 vs. 1.5 ± 0.3 relative expression, p > 0.05) and NF-κB mRNA (5.9 ± 1.9 vs. 2.6 ± 0.6 relative expression, p > 0.05), though these differences did not reach statistical significance. This evidence concerns the gene NFKB1 and acute kidney injury.