Compared to untreated controls, animals in the AKI + IA saline group showed significant upregulation in KIM-1 mRNA (44.2 ± 6.4 vs. 176.2 ± 9.8 relative expression, p < 0.05), TIMP-1 (4.6 ± 1.3 vs. 26.5 ± 2.2 relative expression, p < 0.05), and NGAL (6.7 ± 0.9 vs. 37.0 ± 2.5 relative expression, p < 0.05). This evidence concerns the gene LCN2 and acute kidney injury.