Finally, in the work of Creaney et al., where six human MM cell lines were compared against three primary mesothelial cell culture preparations using iTRAQ® mass spectrometry (isobaric tag for relativeand absolute quantitation) [39], two upregulated proteins were also found in our data, annexin A2 and prelamin-A/C. The gene discussed is ANXA2; the disease is Miyoshi myopathy.