CD4 and neoplasm: Indeed, we observed the preferential infiltration by Mo-MDSC, macrophages and eosinophils among myeloid cell subsets and by CD8+ and CD4+ T cells over Tregs into the tumor tissue of mice treated with CTX + PDL1/2 therapy as compared to the other treatments (Figure 4 G–H, Supplementary Materials Figure S1C–F).