Meanwhile, we explored several interesting circRNAs (novel_circ_0009127, novel_circ_0000628, novel_circ_0011513, novel_circ_0010775, novel_circ_0006981 and novel_circ_0001494), which functioned in NF-kappa B signaling pathway, Hedgehog signaling pathway, ECM-receptor interactions, steroid biosynthesis, glycerolipid metabolism, cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Type II diabetes mellitus, FoxO signaling pathway and VEGF signaling pathway, these all were closely linked to adipocyte differentiation and proliferation. The gene discussed is VEGFA; the disease is type 2 diabetes mellitus.