Among the nine genes that showed consistent changes in both RNA-seq results and qRT-PCR results, Cxcl3 and Mmp12 have been reported to relate to the cell migration ability [35], survival/suppressive activity [36], and the accumulation of MDSCs [37] in different cancer models, while the functions of the other genes in MDSCs have not been reported yet. The gene discussed is CXCL3; the disease is cancer.