SACK1H and amelogenesis imperfecta, type 3A: Nevertheless, FAM83H is the only FAM83 member implicated in amelogenesis, as mutations in FAM83H have been identified in patients with autosomal dominant hypocalcified amelogenesis imperfecta (ADHCAI) [[12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31]].