Analysis of the ACC-TCGA dataset revealed that the TP53 mutated group had significantly higher mRNA expression in CDK1 (p < 0.001), CCNB1 (p < 0.001), CCNB2 (p < 0.001), and AURKA (p < 0.001) compared with the TP53 wild group (Fig 3A, 3B, 3C and 3D). This evidence concerns the gene CCNB1 and adrenal cortex carcinoma.