Hilvo et al. and Kang et al. reported a significantly increased levels of PC 30:0 in ER- and PgR-negative and HER2 tumor subtypes compared with the corresponding ER- and PgR-positive and HER2-negative subtypes [21, 46] in line with the findings for SK-BR-3 in our study. The gene discussed is ESR1; the disease is neoplasm.