ESR1 and triple-negative breast carcinoma: The subtypes are: I) luminal A (ER+, PgR+, HER2-), II) luminal B (ER+, PgR+, HER2-/+), III) HER2-overexpressing (ER-, PgR-,HER2+), IV) triple negative breast cancer (TNBC; ER-, PgR-, HER2-) and, V) normal-like subtype [3–5].