To showcase our method, we evaluate associations between breast cancer susceptibility and SNPs in estrogen receptor alpha (ESR1), fibroblast growth factor receptor 2 (FGFR2), RAD51 homolog B (RAD51B), and TOX high mobility group box family member 3 (TOX3) genes, without access to raw genotype data. This evidence concerns the gene ESR1 and breast carcinoma.