Pathway analysis [gene ontology (GO) analysis21 and gene set variation analysis (GSVA)22] confirmed that the Vδ2 lymphomas had significantly higher expression of pathways involving type I interferon or interferon-γ (IFN-γ) (adjusted P value = 4 × 10−6, 0.04, respectively) (Fig. 2c, d, Supplementary Tables 7 and 8). The gene discussed is IFNG; the disease is lymphoma.