Consistently, bioinformatic analyses of MOB2 mRNA expression data obtained from The Cancer Genome Atlas (TCGA) showed MOB2 mRNA levels were significantly downregulated in GBM samples (n = 165) compared to LGG samples (n = 525) in the TCGA data set (Fig. 1b; p = 3.94e−05, https://tcga-data.nci.nih.gov/tcga/). Here, MOB2 is linked to glioblastoma.