To extend our findings, we examined the effects of NHWD-870 in an orthotopic mouse OC model, in which we intraperitoneally injected A2780 OC cells, alone or together with F4/80+CD11b+CD206+ TAMs isolated from the tumor tissues of OC-bearing donor mice 3 days later (Fig. 4e). The gene discussed is ITGAM; the disease is neoplasm.