Instead, they express constellation of group-defining genes, including Ly6a, Cd34, and Thy1, which have been shown to mark other adult stem cells, such as HSCs, keratinocyte stem cells, cancer stem cells, muscle stem cells etc (Sidney et al., 2014; Wilson et al., 2007; Shaikh et al., 2016; Nakamura et al., 2006). Here, LY6S is linked to cancer.