We first demonstrate that NGFR is the transcriptional target of p73 target by overexpressing p73 in p53-null cancer cell lines HCT116p53−/− and H1299 and performing RT-qPCR and WB analyses, and observed increased NGFR expression at both the mRNA and protein level (Supplementary Figure S2A–C). Here, NGFR is linked to cancer.