Furthermore, ANXA8 expression (HR 2.151, 95% CI 1.299-3.562, p=0.0029) and lymph node metastasis (HR 2.027, 95% CI 1.227-3.348, p=0.0058) were associated with DFS (Table 3). This evidence concerns the gene ANXA8 and metastatic malignant neoplasm in the lymph nodes.