Within the HOXA cluster is a long non-coding RNA, HOTAIRM1, located between HOXA1 and HOXA2. The role of HOTAIRM1 as an oncogenic factor has been described in several cancers 25,26, and the function of HOTAIRM1 as a regulator of the oncogene HOXA1 has been previously described in glioblastoma multiforme 26. This evidence concerns the gene HOXA1 and cancer.