CDKN1A and cervical squamous intraepithelial neoplasia: To determine whether the increase in CIN phenotypes (i.e., micronuclei) following attenuation of the cGAS/STING pathway is primarily attributable to a decrease in p21 levels, we downregulated p21 by using an RNAi approach, and we counted the number of cells with micronuclei.